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This includes: Upper gastrointestinal bleeding bleeding from the stomach, oesophagus or upper small intestine is the most common cause of melena
Dig Dis Sci 2008;53(5):1278-84
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In general, gastrointestinal side effects, especially constipation, may persist even as other symptoms diminish over time and appear to occur less frequently with long-acting GLP-1 RAs [118]
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