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The identification of novel biomarkers, such as melatonin metabolites, oxidative catabolites, DNA methylation patterns, and circulating miRNAs, represents a critical step toward developing reliable tools for early detection and individualized risk stratification 2
2.4 Cell counting Kit-8 (CCK8) assay Cell viability was measured using the CCK-8 (Beyotime, China)
Laser that lightens solar lentigines on fair skin can cause paradoxical darkening on melasma
Routine lab tests often include HbA1c, fasting glucose, insulin levels (HOMA-IR), lipid panels, and kidney function tests
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