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PMCID: Xie Y, Choi T, Al-Aly Z
For detailed guidance on choosing the right probiotic, see our best probiotic for semaglutide guide, which covers strain selection, dosing, and timing in depth
The following side effects (with their frequencies) were reported by participants taking Rybelsus: Nausea (11%) Abdominal pain (10%) Diarrhea (9%) Decreased appetite (6%) Vomiting (6%) Constipation (6%) [1] Similarly, here is a breakdown of Ozempic side effects in clinical trials: Nausea (15.8%) Diarrhea (8.5%) Abdominal pain (7.3%) Vomiting (5%) Constipation (5%) [2] Overall, with side effects so similar, the decision between Ozempic vs Rybelsus for weight loss comes down to patient preferences
That may include checking your thyroid levels after significant weight loss, reviewing the timing of your thyroid medication, and paying attention to side effects that seem out of proportion
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