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In zebrafish, 10 mM lactate treatment for 24 hours significantly increased hepatic lipid content

Monotherapy versus Combination Therapy The decision to initiate drug therapy with metformin alone or in combination with another agent is influenced by HbA1C level and health status when diabetes is newly diagnosed

Compounds targeting metabolic molecular targets Targeting glycolysis 2-deoxy-D-glucose (2-DG) is a well-known glycolysis inhibitor that specifically targets the activity of HK2 [256]