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Side Effects & Safety Transient headache -- the most commonly reported side effect Mild nausea -- usually resolves within 30 minutes Temporary dizziness/vertigo -- reported at higher doses Injection site redness -- standard for SC peptides No lethal dose identified in animal studies No dependency or withdrawal documented No respiratory depression -- unlike pharmaceutical sleep aids DSIP appears on the FDA's list of bulk drug substances that raise potential safety concerns

Oocyte collection and in vitro maturation Immature COCs were retrieved from the follicles using a scalpel blade in 2 mL of collection medium (TCM199 medium supplemented with 2.38 mg/mL HEPES, 2 L/mL heparin, and 4 L/mL gentamicin)

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Department of Health and Human Services and the FDA published guidance for pharmaceutical companies that develop and produce antidiabetic medications