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Weight reduction most likely played a large role in heart health, but researchers are also finding convincing early evidence that GLP-1and the drugsmay reduce inflammation when bound to receptors
Start low: Begin around 250 g daily for 12 weeks Increase gradually: Up to 500 g twice daily if tolerated Cycle: 46 weeks on, then take 24 weeks off This approach supports tendon, muscle, or ligament healing without overloading the system
Ezeria D, Takano Y, Hanaoka K, Urano Y, Dick TP
central to longevity claims but conducted by the originating group, not modern blinded design, and never independently replicated
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