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Genetic alterations are largely stable before and after NAC and are not associated with recurrence Previous studies performed targeted sequencing of EC and mitophagy-related genes to identify SNVs and INDELs, which were subsequently classified as pathogenic or likely-pathogenic variants by consulting ClinVar

For patients with an A1C of 6.5% to 7.5%, metformin is the preferred initial agent, with GLP-1 receptor agonists, dipeptidyl-peptidase-4 (DPP-4) inhibitors, thiazolidinediones (TZDs), or an alpha-glucosidase inhibitor listed as viable alternatives

Jiang K, Moe-Lange J, Hennet L, Feldman LJ (2016) Salt stress affects the redox status of Arabidopsis root meristems