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Description

The above cardiac and extracardiac effects outline the cardioprotective mechanisms of SGLT2 inhibitors that stay behind the success of these drugs in the cardiovascular field

Am J Med 1992;92:77-81

The most commonly observed adverse events (incidence of 5% and twice that of placebo) were oily spotting, flatus with discharge, fecal urgency, fatty/oily stool, oily evacuation, increased defecation and fecal incontinence