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Description

MC-1R is responsible for signaling the body to produce more melanin, the substance responsible for darkening skin and hair

Ann Rheum Dis

Fluoxetine affects embryonic morphogenesis by inhibiting the activity of the Wnt signaling pathway and reducing cell proliferation, and activation of the Wnt signaling pathway partially mitigates the adverse effects of fluoxetine on embryonic morphology through a mechanism of action that is not directly related to the inhibition of serotonin reuptake in the synapse