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Description

Motor cortex cultures P3 motor cortices isolated from WT-UeGFP, and prpTDP-43 A315T UeGFP mice, dissected, dissociated, and cultured on glass coverslips (4 10 4 cells per 18 mm diameter coverslip, Fisherbrand) coated with poly-L-lysine (10 mg/mL, Sigma)

In particular, FKBP12 is a 12-kDa cytosolic protein with peptidylprolyl cistrans isomerase activity, while FKBP-13 is a 13-kDa membrane-associated protein with 43% amino acid identity with FKBP12 (Lai et al., 2010)

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