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However, even with treatment using erythropoiesis-stimulating agents (ESAs) and iron supplements, approximately half of the patients exhibit a hypo-responsive or suboptimal correction of anemia, suggesting the involvement of other significant mechanisms in the development and progression of renal anemia

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"Combination Therapies for Obesity: Cagrilintide and GLP-1 Receptor Agonist Synergy." Nature Reviews Endocrinology, 18(9), 541-556