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TB-500 actin-binding affinity utilises pyrene-actin polymerisation assays, measuring fluorescence changes upon actin filament formation

Efficacy Outcomes MET-097 demonstrated a clear dose-dependent reduction in body weight , with the 1.2 mg dose group achieving a 7.5% mean weight loss from baseline by Day 36

Polyacrylic acid, but not polyethylene glycol, induces metabolic reprogramming linked to pulmonary fibrosis in rats

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