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Watson typically starts patients on liraglutide, which tends to be the gentlest and least expensive of the GLP-1s
JAMA , 333 (8), 652655.
They estimated that people who stopped the drugs would return to their previous weight within about two years
Oral administration is generally ineffective due to gastric peptidase degradation, and intravenous (IV) routes are rarely used outside pharmacokinetic studies due to rapid clearance and the need for continuous infusion to maintain therapeutic levels
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