Material discussed here is intended strictly for laboratory research use only
Warning signs that warrant medical attention include spreading redness, pus, prolonged pain, or fever (possible infection), and new dark or light patches (post-inflammatory pigment change), which is a particular consideration for medium-to-deep skin tones
However, the existence of hypoxia and necrosis also provides an opportunity for tumour-selective therapy, including prodrugs activated by hypoxia, hypoxia-specific gene therapy, targeting the hypoxia-inducible factor 1 transcription factor, and recombinant anaerobic bacteria
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