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If we had a treatment for obesity, they wouldn't have had that' (Hickey)
Results from this trial showed that Miplyffa, in combination with miglustat, halted disease progression through 12 months of treatment, as evidenced by a decrease of 0.2 points from baseline on the rescored 4-domain NPC Clinical Severity Scale
The weight comes back when the medication stops In the STEP 1 trial extension, published in Diabetes, Obesity and Metabolism (Wilding et al., 2022), patients who discontinued semaglutide regained about two-thirds of their lost weight within one year
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