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Ipamorelin is a selective pentapeptide growth hormone secretagogue (GHS) that stimulates pituitary GH release by mimicking ghrelin at the GHSR-1a receptor without the cortisol, prolactin, or ACTH elevation associated with earlier GHRPs, making it the cleanest GH secretagogue in the research literature and the most common partner peptide in CJC-1295/Ipamorelin combination stacks