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( E ) Glomerular filtration rate was measured in Glp1r VSM+/+ and Glp1r VSM/ mice treated acutely with semaglutide (10 g/kg) 30 minutes before a bolus of FITC- sinistrin ( n = 510)

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(1) This is allowed by its structure as it is the shortest functional analog of endogenous GHRH with a C-terminal amidation that may help stabilize the molecule