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To view a copy of this licence, visit About this article Cite this article Kong, YX., Li, ZS., Liu, YB
doi: 10.1002/cbdv.202402248 105 ZhaoJ-WZhaoW-YZhaoMYuL
Dose escalation schedules in GLP-1-based therapies are typically gradual precisely to allow the body to adapt and to minimise GI side effects a principle acknowledged in NICE guidance on approved agents (see NICE TA875)
The result is a compound with dramatically superior pharmacokinetics: once-weekly dosing and 5 the weight loss of pramlintide
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