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Vitamin B12 (cobalamin) is a water-soluble vitamin critical for red blood cell formation, DNA synthesis, neurological function, and energy metabolism

The body usually destroys old or faulty red blood cells in the spleen in a process called hemolysis

Treatment: Rosacea is usually treated with gentler skincare products (such as moisturizers for rosacea), as well as dermatologist-prescribed topical anti-inflammatories, sulfur-based washes, and topical or oral antibiotics, says Dr

The synthesis constitutes a formal total synthesis, since the research groups only prepared the known intermediate cobyric acid, whose chemical conversion to vitamin B 12 was previously reported