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Chemistry Central Journal 8 , 11 (2014)
Gene counts were obtained with the featureCounts function from the Rsubread package 98 with the gtf file corresponding to ENSEMBL version GRC138.97 and parameters set to: isPairedEnd = TRUE and strandSpecific = 2
Top-line data from the CLARITY-Gastric01 study showed sonesitatug vedotin significantly extended overall survival in patients who had received at least two prior lines of therapy and also met a key secondary endpoint in an earlier-line population, although the trial failed to achieve statistical significance for progression-free survival
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