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They are usually taken in supplement form to help with symptoms of deficiency, such as fatigue, anxiety, and memory problems

(5.11) Adverse Reactions/Side Effects Most common adverse reactions (incidence 5%) in adults or pediatric patients aged 12 years and older are: nausea, diarrhea, vomiting, constipation, abdominal pain, dysesthesia, headache, fatigue, dyspepsia, dizziness, abdominal distension, eructation, hypoglycemia in patients with type 2 diabetes, flatulence, gastroenteritis, gastroesophageal reflux disease, and hair loss

This is especially valuable for athletes and bodybuilders aiming to build lean mass while minimizing fat gain

Notably, these advantages persisted irrespective of baseline kidney function, HbA1c levels, BMI, the timing of DM diagnosis, comorbidities and concurrent medication, including immunosuppressants (Fig