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SIRT3 also deacetylates targets such as the chaperone protein Hsp10 and the LON protease, involved in the UPR mt process 98
doi:10.1097/JCN.0000000000000469
Its status is investigational and, in certain countries, diagnostic not therapeutic
Additionally, it was reported that trimetazidine (TMZ), a piperazine derivative, mediated activation of the GSH system and had antioxidant and cytoprotective effects in several myocardial injury models [210,211,212,213]
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