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Commonly prescribed GLP-1 medications include Ozempic (semaglutide) , Mounjaro (tirzepatide) , and their generic alternatives
This synergistic effect is likely why tirzepatide (a dual GIP/GLP-1 agonist) outperforms semaglutide (GLP-1 only) in clinical trials Neuroprotective potential Preclinical research suggests GIP receptor activation may have protective effects on brain neurons, though this requires further human study Glucagon Receptor Activation: Retatrutides Unique Advantage The glucagon receptor is what sets retatrutide apart from every other weight loss medication currently available or in late-stage development
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JAMA 2015;314:68799.ArticlePubMed 44
