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This effect is thought to be mediated through GLP-1 receptors in the cardiovascular system and is generally not clinically significant, though patients with certain arrhythmias or those sensitive to heart rate changes should be monitored
10.1016/s0928-4257(97)89478-8 6 HuangT.ZhangK.SunL.XueX.ZhangC.ShuZ.et al (2015)
This combination approach delivers results faster than either method alone
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