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Among women aged 45-54, prescribing increased more than 180%, with nearly 1 in 20 patients receiving therapy by early 2026
Muscle Loss Prevention in Men on GLP-1 Therapy One of the biggest concerns for men taking semaglutide is losing muscle alongside fata risk that's higher in men than in women because male physiology depends more heavily on lean mass for metabolic function
Both oral and injectable GLP-1s have a long half-life (about one week) I typically recommend stopping them at least 2 weeks before surgery This helps ensure proper nutrition, safer anesthesia, and better healing Weight loss drugs are powerful, but surgery requires your body to be well-nourished
Circulation 136:849870 Honigberg MC, Chang LS, McGuire DK, Plutzky J, Aroda VR, Vaduganathan M (2020) Use of Glucagon-Like Peptide-1 Receptor Agonists in Patients With Type 2 Diabetes and Cardiovascular Disease: A Review
