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The effectiveness of gemcitabine is closely tied to the level of ROS [50]
After PEG modification, it can not only bind closely to albumin, cover the enzymatic hydrolysis site of DPP-4, but also reduce renal excretion, prolong the biological half-life, and achieve the effect of long circulation
An increased risk of thyroid C-cell tumors is noted on the FDA boxed warning
Effects on neurotransmitter systems may support the mood, cognitive, and sleep dysregulation that are near-universal in long COVID
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