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A Phase 1 Study of TH-302, a Hypoxia-targeted Drug, in Patients with Advanced Leukemias
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They found that epithalamin led to a median lifespan extension of between 14% and 32% longer than control subjects
The 143B cells were cultured to 80% confluence, and incubated with 200 M hypoxyprobe and PBS, Ru(II)-OH, NP2, or NP4 (Ru 10 M) under hypoxia condition for 12 h
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