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Treatment with GLP-1 and exendin-4 significantly increased neurite length in cultured DRG neurons, potentially accounting for the increased nerve fibers observed in IBS biopsies [55] (Fig
59 JiaC
Recognizing these GLP-1 non-responders promptly allows clinicians to adjust treatment strategies before patients experience prolonged periods without meaningful results, potentially leading to frustration and treatment abandonment
Treatment of Malignant Schwannoma The treatment of malignant schwannomamore accurately termed malignant peripheral nerve sheath tumor (MPNST)is complex and typically requires a multimodal approach, with surgery as the primary curative modality
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