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The traditional PNT method can reduce mtDNA residue in mice [137]
Both RAW 264.7 cells and peritoneal macrophages were maintained in RPMI 1640 medium supplemented with 10% fetal bovine serum, 5% CO, and 95% air at 37C
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The theory is that lower doses may provide the inflammatory marker reductions documented in research while minimizing GI side effects and metabolic disruption
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