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The test maps 49 peptide variants that influence appetite regulation, insulin signaling, and metabolic rate, allowing PlexusDx physicians to recommend the most cost-effective medication path for your unique biology from day one
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Compared to the first-generation GLP-1R agonist, tirzepatide has three critical improvements: first, many residues in peptide backbone are changed to obtain GIPR-activating activity
Notably, patients who have a genetic deficiency of the enzyme 2-HG dehydrogenase are unable to convert 2-HG back to -KG, and subsequently develop accumulations of the metabolite in the brain
