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(16) Diving deeper, the team sought to unravel the effects of this compound on the contractile dynamics of gastric smooth muscles when exposed to acetylcholine and electrical field stimulation
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Interestingly, berberine activates AMPK by partially inhibiting mitochondrial complex I, which raises the AMP/ATP ratio inside cells a signal that tells the body, "energy is scarce, start burning fat." This is very similar to what happens during caloric restriction or exercise at the cellular level
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