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HGF/c-Met pathway research is relevant in controlled experimental settings because this signaling system is associated with cellular response biology, tissue-level communication, neurotrophic pathway behavior, and synaptic connectivity models
1 2 Journal of Applied Physiology
Monolayers of hiPSC-derived endothelial cells from Alzheimer's patients with PSEN1 and PSEN2 mutations, differentiated with a chemically defined medium, possessed a low TEER, reduced expression of claudin-5, occludin, and ZO1 protein, and impaired glucose transport (Raut et al., 2021)
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