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For example, in certain hereditary kidney diseases, gene editing of iPSCs to introduce pathogenic mutations enables the construction of kidney organoids exhibiting abnormal development and function, facilitating the clarification of genetic mechanisms and improving diagnostic accuracy ( In contrast to hPSC/iPSC-derived kidney organoids used to model developmental and non-neoplastic renal disorders, renal tumor organoids are tissue-derived platforms established directly from patient tumor samples
The booming online market for GLP-1s is giving people cheaper access to weight-loss drugs, but often without regulation or medical guidance
Renal tissues from mice with CaOx crystal kidney injury and from negative control mice were collected for untargeted metabolomics
Sinha 1 , Shruti H
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