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Carnitine administration has been shown to speed the decrease of ammonemia in patients with VPA-induced encephalopathy although a correlation between ammonia concentrations and the clinical condition was not always observed

Exposure to cold temperatures activates production of proteins including RNA-binding motif protein 3 (RBM3), which demonstrates neuroprotective effects and may help maintain muscle mass during periods of reduced activity

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Honokiol ameliorates cigarette smoke-induced damage of airway epithelial cells via the SIRT3/SOD2 signalling pathway