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3 Background Anatomy of the Biliary System The gallbladder is a pear-shaped, muscular, pouch-like organ that is roughly three to six inches long and sits under the liver in the upper right region of the abdomen

Limitations of traditional mechanistic frameworks Traditional models of CVD-cognitive impairment comorbidity primarily focus on vascular-mediated processes, including cerebral hypoperfusion, where arterial stenosis or HF-induced reduction in blood flow impairs the delivery of oxygen and nutrients to neurons

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