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Semaglutide weight loss injections have demonstrated impressive results in clinical trials, with many patients seeing significant weight reduction when combined with healthy lifestyle changes

On December 4, 2025, the JPML heard arguments to create a new multidistrict litigation (MDL), this time for people who lost their vision after taking Zepbound and similar GLP-1 drugs

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However, these observational studies have inherent limitations, including potential residual confounding (as some registries lack complete data on important cancer risk factors like smoking), selection bias, and the challenge of detecting rare events