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Most protocols run for 3 to 6 months, with periodic lab monitoring to track IGF-1 and metabolic markers
Importantly, pregnancy outcomes in recipients receiving oocytes from women with PCOS are comparable to those from healthy donors, suggesting that endometrial dysfunctionrather than oocyte competencyis a major contributor to infertility in PCOS
Hence, there was a suspicion of exendin-4's involvement in the inflammatory process and, indirectly and directly, in atherosclerosis development, which was investigated and then validated
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