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Patients at higher risk for dehydration complications include older adults, individuals with chronic kidney disease, those taking diuretics or other medications affecting fluid balance, and patients with diabetes who may have underlying autonomic dysfunction affecting thirst perception
[16] Given that existing licensed weight management options are available, retatrutide would not typically meet the threshold for EAMS access for obesity
GLP-1 receptor agonists (like semaglutide) and tirzepatide already show benefits in NAFLD/NASH
3.6 Glutamate Glutamate, the enzymatic precursor for GABA, constitutes about 10% of dietary amino acid content
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