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Postural orthostatic tachycardia syndrome (POTS) describes a set of symptoms related to autonomic nervous dysfunction , including nausea, dizziness, increased heart rate, exercise intolerance, and more. Patients with the partial dysautonomic (PD) form dont respond to gravity/postural changes well (moving between laying down and sitting up, standing for long periods of time, etc). Patients with the hyperadrenergic form discuss experiencing significant tremor, anxiety, and cold sweaty extremities while upright

Glutamate toxicity can be reduced by antioxidants, and the psychoactive principle of cannabis, tetrahydrocannabinol (THC), and the non-psychoactive principle cannabidiol (CBD), and other cannabinoids, is found to block glutamate neurotoxicity with a similar potency, and thereby potent antioxidants