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They discovered a protective mechanism by investigating how Chr-Chi NPs mitigate A-induced neurodegenerative diseases
The representative synthetic compound targeting Nrf2 is melatonin, an amine hormone secreted by the brains pineal gland [203]
Consistent with these findings, while NRF2 induces chemoresistance in KRAS-driven cancers, suppressing glutamine metabolism leads to weakened chemoresistance in these cancer cells 85
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