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The enzymes associated with the QA chain, kynurenine 3-monooxygenase (KMO), kynureninase (KYNU), and 3-hydroxyanthranilic acid oxygenase (3-HAO) have their activities increased in the microglia due to pro-inflammatory cytokines
Lastly, NAD plays a key role in the aging process, including reducing genomic instability, addressing mitochondrial dysfunction, and decreasing age-related inflammation
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