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Novo Nordisk has demonstrated that you can get 50 milligrams of oral semaglutide in new formulation and have 15 percent body weight loss. It is not easy to achieve the same level of GLP-1 secretion with other approaches, he said, but some companies are still working to develop effective GLP-1 secretagogues, or substances that cause GLP-1 to be secreted, he said

The incidence of heart failure was reduced by 59%, non-fatal stroke by 27%, and non-fatal heart attack by 47%

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