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In a phase IIa, randomized, open-label study with an active comparator, efinopegdutide was compared with semaglutide over 24 weeks in individuals with elevated liver fat content (LFC)
Quick Answer: No single GLP-1 receptor agonist has been proven superior for anti-inflammatory effects, as these medications are not licensed for treating inflammation in the UK
However, the efficacy of the thymus diminishes over time, which may lead to tissue damage and diminished immunity
Current approaches include: Continuous Use Approach: Based on clinical trials that used continuous daily administration for 12-24 weeks without scheduled breaks
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