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While the study employed a longitudinal pre- and post-treatment design, strict adherence to paired sampling was constrained by logistical factors inherent to the pediatric population

Acknowledgements We appreciate the support from the National Natural Science Foundation of China (82071676, 81703492)

Beyond its proteolytic activity, LONP1 not only acts as a molecular chaperone facilitating protein folding but also directly binds to mitochondrial DNA (mtDNA), suggesting a multifunctional role in mitochondrial genome regulation

Supports Collagen Production: Vitamin C plays a crucial role in collagen synthesis, helping to maintain skin elasticity and firmness, reducing fine lines and wrinkles