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Cravings are mostly a centralized function of the brain. GLP-1 drugs also might help by reducing or delaying the emptying time of the stomach, Hany said

The cross-species studies were reviewed from nematodes to mammals, in which short peptides can modulate the aging-related targets precisely, such as sarco/endoplasmic reticulum (SR/ER) calcium (Ca 2+ )-ATPase (SERCA) pumps and Bcl-2-associated X protein complexes

doi:10.1046/j.0014-2956.2001.02553.x 45