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It is a small molecule, specifically a quinolinium-based selective inhibitor of the NNMT enzyme
The randomized, double-blind, placebo-controlled, multicentre Phase 2 study enrolled 263 adults with obesity or overweight plus at least one obesity-related comorbidity, without type 2 diabetes, and ran 48 weeks
To absorb vitamin B12 effectively, your body requires an intact stomach and gut, a well-functioning pancreas, and sufficiently high levels of intrinsic factor, a protein that binds to vitamin B12 in the stomach (1)
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