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They can help you understand the potential benefits and risks, determine appropriate dosages, and monitor your progress throughout treatment

In this review, we systematically examine the molecular and cellular determinants of drug response and resistance across 22 cancer types, highlighting key resistance mechanisms such as compensatory pathway activation, phenotypic plasticity, immune evasion, enhanced DNA damage repair, and the survival of drug-tolerant persister cells

M2-like TAMs, which dominate many solid tumors, create a ferroptosis-resistant niche by exporting iron through ferroportin, supplying cysteine precursors that support glutathione synthesis, and releasing IL-10, TGF-, and lipid mediators that dampen oxidative stress

Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion