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Human immunodeficiency virus (HIV) antivirals such as the protease inhibitors Prezista (darunavir), fosamprenavir, and Aptivus (tipranavir) Carbonic anhydrase inhibitors such as acetazolamide used to treat glaucoma (increased eye pressure), epilepsy, and high-altitude sickness Loop diuretics (used to manage heart failure) such as Bumex (bumetanide) and Lasix (furosemide) Sulfonylureas (used to manage diabetes) such as Glucotrol (glipizide) and glyburide COX-2 inhibitors (an anti-inflammatory) such as Celebrex (celecoxib) Triptans (used to manage migraines) such as Imitrex (sumatriptan) Thiazide diuretics (used to manage heart failure and high blood pressure) such as Thalidone (chlorthalidone) and hydrochlorothiazide Azulfidine (sulfasalazine) (used for inflammatory bowel disease and rheumatoid arthritis) Antibiotics Without Sulfa There are many non-sulfa antibiotics available as alternatives to sulfa-containing drugs

(ii) It responds with a single pulse to a step function and with multiple pulses during a continuous gradual increase in the stimulus concentration (Fig 2A

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