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High-dose antioxidant therapy during thrombolysis in patients with acute myocardial infarction
Moreover, these tumors express significant amounts of glutaminase (GLS) [21], being able to fully metabolize glutamine that will serve as a substrate to supply bioenergetic and biosynthetic circuitries crucial for GBM cell survival [22,23,24,25]
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Other intermembrane proteins released into the cytosol such as cytochrome c and Smac/DIABLO, do not promote apoptosis because APAP-induced mitochondrial dysfunction and oxidant stress prevents any apoptotic signaling in hepatocytes [54, 55]
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