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Healthcare Materials 13, e2303229
After 52 weeks, 26% and 30% of participants who received 80 mg and 100 mg of resmetirom, respectively, achieved MASH resolution with no fibrosis worsening compared to 10% on placebo ( p 10 million patient-years of exposure in diabetes and obesity [4, 35]
Songs research on non-small cell lung cancer (NSCLC) found that there is ferroptosis in cancer cells treated with cisplatin, and ferroptosis-resistant cancer cells could secrete miR-4443 through exosomes, which increase the expression of FSP1 in ferroptosis-sensitive cancer cells, thereby enhancing the resistance of the cancer cells to ferroptosis [29]
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